Ọrịa strok, ọrịa na-emebi ihe nke a na-akpọ mbelata ọbara na akwara ụbụrụ n'ihi ọrịa ọbara ọgbụgba ma ọ bụ ọrịa ischemic, bụ ihe nke abụọ kacha akpata ọnwụ n'ụwa niile na nke atọ kacha akpata nkwarụ. Ụdị ọrịa strok abụọ bụ isi bụ ọrịa strok ischemic (nke ruru 68%) na ọrịa strok hemorrhagic (32%). N'agbanyeghị ụdị ọrịa strok ha dị iche na nke mbụ, ha abụọ na-eduga na mbelata ọbara na-ekesa n'ime ụbụrụ na-esote n'oge usoro subacute na nke na-adịghị ala ala.
Ọrịa strok Ischemic
A na-ahụ ọrịa strok Ischemic (AIS) site na mkpọchi mberede nke arịa ọbara, na-ebute mmebi nke ischemic na mpaghara ahụ metụtara. N'oge nnukwu, gburugburu hypoxic a bụ isi na-akpalite oke excitotoxicity, nrụgide oxidative, na mkpali nke microglia, na-eduga na ọnwụ akwara ozi gbasaa. N'oge subacute, ntọhapụ nke cytokines, chemokines, na matrix metalloproteinases (MMPs) nwere ike itinye aka na mbufụt neuroinflammation. Nke pụtara ìhè bụ na ọkwa MMP dị elu na-eme ka mgbochi ọbara-ụbụrụ (BBB) dịkwuo elu, na-ekwe ka mbugharị leukocyte banye na mpaghara infarcted, na-eme ka ọrụ mkpali ka njọ.
Ọgwụgwọ Ugbu a maka Ọrịa strok Ischemic
Ọgwụgwọ kachasị dị irè maka AIS gụnyere thrombolysis na thrombocytosis. Thrombolysis nke a na-etinye n'ime eriri afọ nwere ike ịba uru nye ndị ọrịa n'ime awa 4.5, ebe ọgwụgwọ mbụ na-aghọ uru ka ukwuu. Ma e jiri ya tụnyere thrombolysis, thrombocytosis mechanical nwere windo ọgwụgwọ sara mbara. Na mgbakwunye, ọgwụgwọ ndị na-abụghị ọgwụ, ndị na-abụghị ịwa ahụ dịkaọgwụgwọ oxygen, acupuncture, na mkpali eletriki na-enweta mmetụta dịka ọgwụgwọ mgbakwunye na usoro ọdịnala.
Isi ihe dị mkpa nke Hyperbaric Oxygen Treatment (HBOT)
N'ọnọdụ nrụgide dị n'oké osimiri (1 ATA = 101.3 kPa), ikuku anyị na-eku ume nwere ihe dị ka 21% oxygen. N'ọnọdụ ahụike, oke oxygen agbazere agbaze na plasma dị obere, naanị ihe dị ka 0.29 mL (0.3%) kwa 100 mL nke ọbara. N'ọnọdụ hyperbaric, iku ume 100% oxygen na-eme ka ọkwa oxygen agbazere agbaze na plasma dịkwuo elu nke ukwuu - ruo 3.26% na 1.5 ATA na 5.6% na 2.5 ATA. Ya mere, HBOT na-achọ ime ka akụkụ a nke oxygen agbazere agbaze dịkwuo mma, nke ọma.mmụba nke mkpokọta oxygen n'ime anụ ahụ na mpaghara ischemic. N'oge nrụgide dị elu, oxygen na-agbasa ngwa ngwa n'ime anụ ahụ hypoxic, na-erute ebe mgbasa ozi dị ogologo ma e jiri ya tụnyere nrụgide ikuku nkịtị.
Ruo taa, HBOT ahụla ọtụtụ ojiji maka ọrịa strok ischemic na hemorrhagic. Nnyocha na-egosi na HBOT na-enye mmetụta neuroprotective site na ọtụtụ usoro molekul, biochemical, na hemodynamic dị mgbagwoju anya, gụnyere:
1. Mmụba nke ikuku oxygen n'ime akwara, na-eme ka ikuku oxygen na-abanye n'ime akwara ụbụrụ ka mma.
2. Ịkwụsi ike nke BBB, na-ebelata ọzịza ụbụrụ.
3. Mmelite nke ụbụrụmgbasa ozi microcirculation, na-eme ka metabolism ụbụrụ na mmepụta ike dịkwuo mma ebe a na-ejigide homeostasis nke ion sel.
4. Nhazi nke ọbara n'ime ụbụrụ iji belata nrụgide intracranial ma belata ọzịza ụbụrụ.
5. Mbelata nke mbufụt neuroinflammation mgbe ọrịa strok gasịrị.
6. Mgbochi nke apoptosis na necrosisna-esochi ọrịa strok.
7. Mbelata nrụgide oxidative na igbochi mmerụ ahụ reperfusion, nke dị oke mkpa na ọrịa strok pathophysiology.
8. Nnyocha na-egosi na HBOT nwere ike ibelata vasospasm mgbe ọbara ọgbụgba subarachnoid aneurysmal (SAH) gasịrị.
9. Ihe akaebe na-akwadokwa uru nke HBOT n'ịkwalite neurogenesis na angiogenesis.
Mmechi
Ọgwụgwọ oxygen Hyperbaric na-enye ụzọ dị mma maka ọgwụgwọ ọrịa strok. Ka anyị na-aga n'ihu na-akọwa ihe mgbagwoju anya nke mgbake ọrịa strok, nyocha ndị ọzọ ga-adị mkpa iji mee ka nghọta anyị banyere oge, usoro, na usoro nke HBOT dịkwuo mma.
Na nchịkọta, ka anyị na-enyocha uru nke ọgwụgwọ oxygen hyperbaric maka ọrịa strok, o doro anya na iji ọgwụgwọ a eme ihe nwere ike ịgbanwe ụzọ anyị si ejikwa ọrịa strok ischemic, na-enye olileanya nye ndị ọrịa a metụtara.
Ọ bụrụ na ị nwere mmasị inyocha ọgwụgwọ oxygen hyperbaric dị ka ọgwụgwọ nwere ike isi gwọọ ọrịa strok, anyị na-akpọ gị òkù ka ị gaa na weebụsaịtị anyị ka ịmatakwu gbasara ụlọ oxygen hyperbaric anyị dị elu. Site na ọtụtụ ụdị emere maka ojiji ụlọ na nke ọkachamara, MACY-PAN na-enye ngwọta ndị na-enye ọgwụgwọ oxygen dị elu, nke ezubere iche iji kwado njem ahụike na mgbake gị.
Chọpụta ngwaahịa anyị na otu ha ga-esi mee ka ọdịmma gị ka mma nawww.hbotmacypan.com.
Oge ozi: Febụwarị-18-2025